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Poly(ADP-Ribose) Polymerase: Methods and Protocols (Methods in Molecular Biology, 2609)

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Management number 233410484 Release Date 2026/06/27 List Price US$79.26 Model Number 233410484
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This detailed volume explores poly(ADP-ribose) polymerases (PARPs) in the biology of eukaryotes and their relevance to human health. Beginning with a section on the detection and quantification of poly(ADP-ribose) polymer (pADPr), the book continues by delving into the identification of protein targets, functional analysis, the poly(ADP-ribosyl)ating pathway in chromatin and genes expression, as well as the use of animal models and PARP1 inhibitor design and testing, and more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Poly(ADP-Ribose) Polymerase: Methods and Protocols, Third Edition presents essential new and classical methods for studying the pADPr-pathway. Read more

ISBN10 1071628909
ISBN13 978-1071628904
Edition Third Edition 2023
Language English
Publisher Humana
Dimensions 7 x 1 x 10 inches
Item Weight 2.24 pounds
Print length 461 pages
Part of series Methods in Molecular Biology
Publication date December 15, 2022

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